BizTalk interface was failing on writing to the system event log -
System.Diagnostics.EventLog.WriteEntry("BizTalk orchestration", Message, System.Diagnostics.EventLogEntryType.Error);
To solve - I set full permissions for the
BtsInstanceHost account (or account which used for BizTalkServerApplication logon) on
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\EventLog registry key.
Sometimes
FILE adapter fails to pool file from the directory; As well - giving full permissions on the folder to BtsInstanceHost solves the problem.